The finding suggest that aging is not simply the result of one specific gene or pathway acting on its own, but rather combinations of genes or pathways interacting with each other, which may explain why no single specific gene that extends longevity in humans has been found.
Mutations in the β-globin gene, the essential component of adult hemoglobin (HbA; α2β2), results in either a production of aberrant sickle hemoglobin leading to sickle cell disease or an insufficie...
The CRISPR/Cas9 gene editing system has been widely used in the basic biomedical research. However, the preclinical safety of the CRISPR/Cas9 system lacks a comprehensive assessment. Previous studies ...
In late October 2019, a Harvard University-led team have elaborated the molecular and neural mechanisms of pheromone-related learning behaviors in C. elegans. A pheromone is known as a secreted or exc...
Researchers in University of Pittsburgh demonstrated that C. elegans missing TCER-1 protein, a homolog of human TCERG1, fight off bacterial infections better than ones with intact gene. TCER-1 is foun...
Researches by a Princeton University-led team have observed that C. elegans can transmit complex learned avoidance behaviors from parent to progeny via eggs and sperm cells, giving the offspring an inherited mechanism for surviving dangerous conditions.
According to a study published in Nature, titled Genetic variation in glia–neuron signalling modulates ageing rate, the genetic variation of a newly discovered signaling pathway affects the aging rat...
Professor Gilula Chair of Scripps Research and senior research author Dr. Benjamin Cravatt declare a new proposal of life extension pathway by interfering/suppressing of specific enzyme-associated pat...
Nematodes are the most abundant animals on the blue planet, filling all trophic levels in the soil food web. Knowing where these tiny worms live matters because nematodes play a critical role in the c...
