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The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

2019-10-24 17:05

Researchers in University of Pittsburgh demonstrated that C. elegans missing TCER-1 protein, a homolog of human TCERG1, fight off bacterial infections better than ones with intact gene. TCER-1 is found out to play a role in suppressing immune response in C. elegans. By removing tcer-1 gene, present more active immune systems and they are able to carry out better resistance to infections and even environmental stress such as heat, radiation, etc. Instead, C. elegans show the loss of longevity. This seems like a novel discovery but brings out a caution to scientists that unexpected frailty will eventually show up in nowhere when altering the nature.

Check more details on Nature: https://www.nature.com/articles/s41467-019-10759-z